On Twitter, pope to get different type of followers
















VATICAN CITY (Reuters) – Pope Benedict already has 1.2 billion “followers” in the standard sense of the word but he soon will have another type when he enters what for any 85 year old is the brave new world of Twitter.


Vatican officials say the pontiff, who is known not to love computers and still writes most of his speeches by hand, will have his own handle by the end of the year.













“It will be an officially verified channel,” said a Vatican official.


Primarily the tweets will come from the contents of his weekly general audience, Sunday blessings and homilies on major Church holidays. They will also include reaction to major world events, such as natural disasters.


The leader of the world’s 1.2 billion or so Roman Catholics will not, of course, write the tweets himself, but he will sign off on them before they are sent in his name.


But even divine intervention might not help squeeze the gist of a papal encyclical, which can run to more than 140 pages, into 140 characters.


Those tweets will probably be limited to a link to a url with the entire document.


The papal handle has not yet been disclosed but it is widely expected to be @BenedictusPPXVI, his name and title in Latin.


The pope has given a qualified blessing to social networking.


In a document issued last year, he said the possibilities of new media and social networks offered “a great opportunity”, but warned of the risks of depersonalisation, alienation, self-indulgence, and the dangers of having more virtual friends than real ones.


In 2009, a new Vatican website, www.pope2you.net, went live, offering an application called “The pope meets you on Facebook”, and another allowing the faithful to see the pontiff’s speeches and messages on their iPhones or iPods.


The Vatican famously got egg on its face in 2009 when it was forced to admit that, if it had surfed the web more, it might have known that a traditionalist bishop whose excommunication was lifted had for years been a Holocaust denier.


(Reporting By Philip Pullella; editing by Mike Collett-White)


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Ghana building collapse traps dozens, kills 1
















ACCRA, Ghana (AP) — A five-story shopping center built earlier this year in a bustling suburb of Ghana‘s capital collapsed Wednesday, killing at least one person and leaving several dozen people trapped in the rubble, authorities and eyewitnesses said.


Rescue crews used cranes to try and remove debris from the top of the building amid fears that machinery sifting through the wreckage could injure trapped survivors. Crowds of bystanders gathered as rescuers sifted through cement and glass.













The fatality at the Melcom Shopping Center at Achimota, a suburb of Accra, was confirmed by Public Affairs Officer of the Ghana Fire Service Billy Anaglate. “We are still working to find out the fate of others who may be trapped under,” he said.


Other officials told The Associated Press that the death toll was likely to rise.


An AP reporter at the scene saw at least one man pulled from the debris, covered in dust and who was then whisked into an ambulance.


A Greater Accra Regional Public Affairs officer, deputy superintendent Freeman Tettey, confirmed that one person died and told the AP that 51 have been rescued and sent to hospitals around the capital.


“I was on my way to the shop when l saw it crumpling down,” Kojo Boadi, an eyewitness, said.


President John Mahama declared the scene a disaster zone and cut short his election campaign in the north of the country to be able to visit the site. The presidential election is scheduled for December.


The five-story store opened in February is part of the Melcom chain owned by Indian immigrant magnate, Bhagwan Khubchandani. His late father arrived in Ghana in 1929 as a 14-year-old to work as a store boy in the-then Gold Coast.


The store sells a variety of cheap, imported household goods and appliances that are popular with working-class Ghanaians.


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Exclusive: Google Ventures beefs up fund size to $300 million a year

SAN FRANCISCO (Reuters) - Google will increase the cash it allocates to its venture-capital arm to up to $300 million a year from $200 million, catapulting Google Ventures into the top echelon of corporate venture-capital funds.


Access to that sizeable checkbook means Google Ventures will be able to invest in more later-stage financing rounds, which tend to be in the tens of millions of dollars or more per investor.


It puts the firm on the same footing as more established corporate venture funds such as Intel's Intel Capital, which typically invests $300-$500 million a year.


"It puts a lot more wood behind the arrow if we need it," said Bill Maris, managing partner of Google Ventures.


Part of the rationale behind the increase is that Google Ventures is a relatively young firm, founded in 2009. Some of the companies it backed two or three years ago are now at later stages, potentially requiring larger cash infusions to grow further.


Google Ventures has taken an eclectic approach, investing in a broad spectrum of companies ranging from medicine to clean power to coupon companies.


Every year, it typically funds 40-50 "seed-stage" deals where it invests $250,000 or less in a company, and perhaps around 15 deals where it invests up to $10 million, Maris said. It aims to complete one or two deals annually in the $20-$50 million range, Maris said.


LACKING SUPERSTARS


Some of its investments include Nest, a smart-thermostat company; Foundation Medicine, which applies genomic analysis to cancer care; Relay Rides, a carsharing service; and smart-grid company Silver Spring Networks. Last year, its portfolio company HomeAway raised $216 million in an initial public offering.


Still, Google Ventures lacks superstar companies such as microblogging service Twitter or online bulletin-board company Pinterest. The firm's recent hiring of high-profile entrepreneur Kevin Rose as a partner could help attract higher-profile deals.


Soon it could have even more cash to play around with. "Larry has repeatedly asked me: 'What do you think you could do with a billion a year?'" said Maris, referring to Google chief executive Larry Page.


(Editing by Muralikumar Anantharaman)


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Cancer trials can lack clear information on biopsies
















NEW YORK (Reuters Health) – People participating in cancer drug trials aren’t always given the most straightforward explanation of possible risks and benefits from invasive procedures that may be involved, according to a new study.


Biopsies of tumor tissue can help researchers figure out how well a test drug is working – but the invasive, sometimes painful procedures are typically of little benefit to study participants themselves.













The new findings show more than five percent of biopsies in such trials may result in complications, but that informed consent documents spend less time explaining those risks than they do for simple blood draws, which are much less invasive.


“Most of these procedures don’t have any therapeutic value for patients, they are burdensome, they’re painful and they carry risk,” said Jonathan Kimmelman, from the Biomedical Ethics Unit at McGill University in Montreal, Canada.


“Before you do a procedure like that on patients, you really want to have their adequate informed consent,” Kimmelman, who wasn’t involved in the new study, told Reuters Health.


“The only reason (patients) should submit to them is to contribute to science in some way,” and not with the hope the biopsies will help them get better, he said.


For the new study, researchers from the University of Texas MD Anderson Cancer Center in Houston reviewed 57 cancer trials by their institution that involved tumor biopsies for study subjects and were conducted in 2005 through 2010.


In 38 of those trials, a biopsy was mandatory for all participants, often as a way for researchers to tell if the drug in question had worked as intended. In some other cases, biopsies were used as pre-study checks to see if patients had the right type of tumor for a certain targeted drug.


Lead author Dr. Michael Overman and his colleagues found almost all informed consent documents didn’t specifically address the research alternatives to biopsies or the lack of likely benefits for patients themselves. The average document had just 39 words addressing the potential risks from study biopsies, compared to 48 words for blood draws.


In those trials, 576 patients had a total of 745 tumor biopsies – including lung, liver and head and neck biopsies. Thirty-nine of those resulted in complications, such as lung air leaks and bleeding, and six in major complications requiring patients to be hospitalized or to get further surgery, according to findings published Monday in the Journal of Clinical Oncology.


Overman said one of the problems has been that until now, there hasn’t been enough available data for study investigators to give patients a reliable estimate of their chance of a biopsy-related complication.


“The informed consent documents that are used are not always as clear as they could be,” Kimmelman said.


He added that not all cancer studies requiring biopsies are of the highest quality. And some don’t make it into the published scientific literature, where they could potentially help determine if a drug is approved or could guide treatment decisions for future patients.


“I think a lot of patients understandably think that when they’re volunteering for these studies they’re giving tissue for what is cutting-edge science, and sometimes that’s true, but not always,” Kimmelman said.


Both researchers agreed that as more targeted drugs are designed for patients with very specific types of cancer, research biopsies will become increasingly necessary to determine how well those drugs are working on the tumor itself.


“I think giving biopsies is a good thing. I think you learn from it, but you need to do it in an honest fashion,” Overman told Reuters Health.


Especially in early drug studies, the patients involved typically have few established treatment options.


“This is where we should say (to patients), ‘This is an experimental therapy, an experimental biopsy, and you don’t have to do it,’” Overman said.


SOURCE: http://bitly.com/U9NXK1 Journal of Clinical Oncology, online November 5, 2012.


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Loughner gets life for deadly Ariz. rampage

TUCSON, Ariz. (AP) — The man who pleaded guilty to a deadly Arizona shooting rampage that wounded former U.S. Rep. Gabrielle Giffords was sentenced to life in prison Thursday.


U.S. District Judge Larry Burns sentenced 24-year-old Jared Lee Loughner for the January 2011 attack that left six people dead and Giffords and others wounded.


Loughner pleaded guilty to federal charges under an agreement that guarantees he will spend the rest of his life in prison without the possibility of parole.


The hearing marked the first time victims — including Giffords — could confront Loughner in court.


Her astronaut husband, Mark Kelly, did all the talking for her, as the couple looked at Loughner and told him how his deadly rampage at the former congresswoman's political meeting had upended her life.


"Her life has been forever changed. Plans she had for our family and her career have been immeasurably altered," Kelly said. "Every day is a continuous struggle to do those things she once was so good at."


Loughner showed no emotion, and looked at the other victims. His mother sobbed nearby.


"Mr. Loughner, you may have put a bullet through her head but you haven't put a dent in her spirit and her commitment to make the world a better place," Kelly said.


Giffords kissed Kelly when he was done. He grabbed her hand and they walked away, with her limping.


Earlier, Loughner told Burns that he will not be speaking at the hearing.


Loughner pleaded guilty three months ago to 19 federal charges under an agreement that guarantees he will spend the rest of his life in prison without the possibility of parole.


Both sides reached the deal after a judge declared that Loughner was able to understand the charges against him. After the shooting, he was diagnosed with schizophrenia and underwent forcible psychotropic drug treatments.


At the hearing, Loughner, who wore dress pants and a dark brown shirt with a tie, heard from his victims.


"We've been told about your demons, about the illness that skewed your thinking," said Susan Hileman, at times visibly shaking, to Loughner. "Your parents, your schools, your community, they all failed you.


"It's all true," Hileman said. "It's not enough."


"You pointed a weapon and shot me three times," she said, staring directly at Loughner. He looked back at her. "And now I walk out of this courtroom and into the rest of my life and I won't think of you again."


Some victims, including Giffords, welcomed the plea deal as a way to move on. It spared victims and their families from having to go through a potentially lengthy and traumatic trial and locks up the defendant for life.


Christina Pietz, the court-appointed psychologist who treated Loughner, had warned that although Loughner was competent to plead guilty, he remained severely mentally ill and his condition could deteriorate under the stress of a trial.


When Loughner first arrived at a Missouri prison facility for treatment, he was convinced Giffords was dead, even though he was shown a video of the shooting. He eventually realized she was alive after he was forcibly medicated.


It's unknown whether Pima County prosecutors, who have discretion on whether to seek the death penalty against Loughner, will file state charges against him. Stephanie Coronado, a spokeswoman for Pima County Attorney Barbara LaWall, said Wednesday that no decision had been made.


It's unclear where Loughner will be sent to serve his federal sentence. He could return to a prison medical facility like the one in Springfield, Mo., where he's been treated for more than a year. Or he could end up in a prison such as the federal lockup in Florence, Colo., that houses some of the country's most notorious criminals, including Oklahoma City bombing conspirator Terry Nichols and "Unabomber" Ted Kaczynski.

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Exclusive: Google Ventures beefs up fund size to $300 million a year

SAN FRANCISCO (Reuters) - Google will increase the cash it allocates to its venture-capital arm to up to $300 million a year from $200 million, catapulting Google Ventures into the top echelon of corporate venture-capital funds.


Access to that sizeable checkbook means Google Ventures will be able to invest in more later-stage financing rounds, which tend to be in the tens of millions of dollars or more per investor.


It puts the firm on the same footing as more established corporate venture funds such as Intel's Intel Capital, which typically invests $300-$500 million a year.


"It puts a lot more wood behind the arrow if we need it," said Bill Maris, managing partner of Google Ventures.


Part of the rationale behind the increase is that Google Ventures is a relatively young firm, founded in 2009. Some of the companies it backed two or three years ago are now at later stages, potentially requiring larger cash infusions to grow further.


Google Ventures has taken an eclectic approach, investing in a broad spectrum of companies ranging from medicine to clean power to coupon companies.


Every year, it typically funds 40-50 "seed-stage" deals where it invests $250,000 or less in a company, and perhaps around 15 deals where it invests up to $10 million, Maris said. It aims to complete one or two deals annually in the $20-$50 million range, Maris said.


LACKING SUPERSTARS


Some of its investments include Nest, a smart-thermostat company; Foundation Medicine, which applies genomic analysis to cancer care; Relay Rides, a carsharing service; and smart-grid company Silver Spring Networks. Last year, its portfolio company HomeAway raised $216 million in an initial public offering.


Still, Google Ventures lacks superstar companies such as microblogging service Twitter or online bulletin-board company Pinterest. The firm's recent hiring of high-profile entrepreneur Kevin Rose as a partner could help attract higher-profile deals.


Soon it could have even more cash to play around with. "Larry has repeatedly asked me: 'What do you think you could do with a billion a year?'" said Maris, referring to Google chief executive Larry Page.


(Editing by Muralikumar Anantharaman)


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Giffords' husband faces shooter in court

TUCSON, Ariz. (AP) — Gabrielle Giffords came face to face Thursday with the man who tried to kill her last year, but chose not to speak.


Her astronaut husband, Mark Kelly, did all the talking for her, as the couple told Jared Lee Loughner how the 24-year-old's deadly rampage at the former congresswoman's political meeting had upended her life.


"Her life has been forever changed. Plans she had for our family and her career have been immeasurably altered," Kelly said at Loughner's sentencing. "Every day is a continuous stuggle to do those things she once was so good at."


Loughner showed no emotion, and looked at the other victims. His mother sobbed nearby.


"Mr. Loughner, you may have put a bullet through her head but you haven't put a dent in her spirit and her commitment to make the world a better place," Kelly said.


Giffords kissed Kelly when he was done. He grabbed her hand and they walked away, with her limping.


Earlier, Loughner told U.S. District Judge Larry Burns that he will not be speaking at the hearing where he is expected to be sentenced to life in prison.


Loughner pleaded guilty three months ago to 19 federal charges under an agreement that guarantees he will spend the rest of his life in prison without the possibility of parole. The deal calls for the dismissal of 30 other charges and a sentence of seven consecutive life terms, followed by 140 years in prison.


Both sides reached the deal after a judge declared that Loughner was able to understand the charges against him. After the shooting, he was diagnosed with schizophrenia and underwent forcible psychotropic drug treatments.


At the hearing, Loughner, who wore dress pants and a dark brown shirt with a tie, heard from his victims.


"We've been told about your demons, about the illness that skewed your thinking," said Susan Hileman, at times visibly shaking, to Loughner. "Your parents, your schools, your community, they all failed you.


"It's all true," Hileman said. "It's not enough."


"You pointed a weapon and shot me three times," she said, staring directly at Loughner. He looked back at her. "And now I walked out of this courtroom and into the rest of my life and I won't think of you again."


Some victims, including Giffords, welcomed the plea deal as a way to move on. It spared victims and their families from having to go through a potentially lengthy and traumatic trial and locks up the defendant for life.


Christina Pietz, the court-appointed psychologist who treated Loughner, had warned that although Loughner was competent to plead guilty, he remained severely mentally ill and his condition could deteriorate under the stress of a trial.


When Loughner first arrived at a Missouri prison facility for treatment, he was convinced Giffords was dead, even though he was shown a video of the shooting. He eventually realized she was alive after he was forcibly medicated.


It's unknown whether Pima County prosecutors, who have discretion on whether to seek the death penalty against Loughner, will file state charges against him. Stephanie Coronado, a spokeswoman for Pima County Attorney Barbara LaWall, said Wednesday that no decision had been made.


It's unclear where Loughner will be sent to serve his federal sentence. He could return to a prison medical facility like the one in Springfield, Mo., where he's been treated for more than a year. Or he could end up in a prison such as the federal lockup in Florence, Colo., that houses some of the country's most notorious criminals, including Oklahoma City bombing conspirator Terry Nichols and "Unabomber" Ted Kaczynski.

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FDA reviewing Merck’s experimental insomnia drug
















WHITEHOUSE STATION, N.J. (AP) — Drugmaker Merck & Co. says the Food and Drug Administration is reviewing its experimental insomnia medication, suvorexant (SOO’vor-eks-ant).


The drug minimizes the morning grogginess common with many sleep aids. It could become a big seller for the Whitehouse Station, N.J., company.













If approved, it would be the first in a new class of medicines for patients with trouble falling or staying asleep. It works by temporarily blocking chemical messengers that keep people awake.


The FDA is doing a standard review, which usually takes 10 months. If approved, suvorexant would be a controlled substance like all hypnotic sleep drugs. They require additional government reviews taking four months or longer.


In studies, suvorexant’s most common side effects were tiredness and headache.


Merck also plans to seek approval for suvorexant in other countries.


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Ghana building collapse traps dozens, kills 1
















ACCRA, Ghana (AP) — A five-story shopping center built earlier this year in a bustling suburb of Ghana‘s capital collapsed Wednesday, killing at least one person and leaving several dozen people trapped in the rubble, authorities and eyewitnesses said.


Rescue crews used cranes to try and remove debris from the top of the building amid fears that machinery sifting through the wreckage could injure trapped survivors. Crowds of bystanders gathered as rescuers sifted through cement and glass.













The fatality at the Melcom Shopping Center at Achimota, a suburb of Accra, was confirmed by Public Affairs Officer of the Ghana Fire Service Billy Anaglate. “We are still working to find out the fate of others who may be trapped under,” he said.


Other officials told The Associated Press that the death toll was likely to rise.


An AP reporter at the scene saw at least one man pulled from the debris, covered in dust and who was then whisked into an ambulance.


A Greater Accra Regional Public Affairs officer, deputy superintendent Freeman Tettey, confirmed that one person died and told the AP that 51 have been rescued and sent to hospitals around the capital.


“I was on my way to the shop when l saw it crumpling down,” Kojo Boadi, an eyewitness, said.


President John Mahama declared the scene a disaster zone and cut short his election campaign in the north of the country to be able to visit the site. The presidential election is scheduled for December.


The five-story store opened in February is part of the Melcom chain owned by Indian immigrant magnate, Bhagwan Khubchandani. His late father arrived in Ghana in 1929 as a 14-year-old to work as a store boy in the-then Gold Coast.


The store sells a variety of cheap, imported household goods and appliances that are popular with working-class Ghanaians.


Africa News Headlines – Yahoo! News



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UK PM warns of witch-hunt against gays in pedophile scandal
















LONDON (Reuters) – British Prime Minister David Cameron warned on Thursday that speculation about the identity of an unidentified member of his ruling Conservative party accused of sexually abusing children could turn into a witch-hunt against gay people.


Cameron, who leads a troubled two-party coalition, ordered an investigation this week after a victim of child sexual abuse in Wales said a prominent Conservative political figure had abused him during the 1970s.













The claims, which follow the unmasking of late BBC star presenter Jimmy Savile as one of Britain’s most prolific sex offenders, have stoked concern that a powerful pedophile ring may have operated in Britain in the 1970s and 1980s.


“I have heard all sorts of names bandied around and what then tends to happen is of course that everyone then sits around and speculates about people, some of whom are alive, some of whom are dead,” Cameron said during an ITV television interview.


“It is very important that anyone who has got any information about any pedophile no matter how high up in the country go to the police,” he said.


Britain’s interior minister warned lawmakers this week that if they named suspected child abusers in parliament they risked jeopardizing future trials.


MPs benefit from “parliamentary privilege” – meaning they can speak inside parliament freely without fear of legal action on a host of legally sensitive issues that might otherwise attract lawsuits.


Reports of child abuse have provoked fevered speculation on the Internet about the identity of the Conservative figure from the era of Margaret Thatcher, prime minister from 1979 to 1990.


When the ITV interviewer passed Cameron a piece of paper with the names of people identified on the Internet as being alleged child abusers, Cameron said:


“There is a danger if we are not careful that this could turn into a sort of witch-hunt particularly against people who are gay.”


“I am worried about the sort of thing you are doing right now – giving me a list of names you have taken off the Internet,” Cameron said.


The BBC aired a program last week in which Steven Messham, one of hundreds of victims of sexual abuse at children’s care homes in Wales over two decades, said he had been sexually abused by a prominent Conservative political figure.


However, the BBC reporter said he could not name the figure because there was “simply not enough evidence to name names”.


(Reporting by Guy Faulconbridge; Editing by Andrew Osborn)


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