Black Friday starts on Thursday right after Thanksgiving dinner


Black Friday is the Super Bowl of retail, but some of the nation's largest big-box stores can't wait until the day after Thanksgiving to open their doors to shoppers eager to grab great deals the same day as their turkey dinner.



Traditional Black Friday door-busting deals now start tonight, on what's been dubbed Gray Thursday. Major retail stores such as Kmart, Toys R Us, Walmart and Sears will open their doors beginning at 8 p.m. Target will join the party an hour later.



"It's traditionally been the day after Thanksgiving when the stores go into the black, where they make all their money. But that's not true anymore," retail expert Michelle Madhock said.





With Black Friday sales starting Thursday, that means lines started forming Wednesday, or in some extreme cases a week before as bargain hunters tried to get a turkey leg up on their competition.



Luciana Pendleton pitched a tent outside a Deptford Township, N.J., Best Buy Monday fully equipped with all she needed to spend the next few days away from home so she could be first in line when the doors open.



"I am just happy I beat my competition. They pulled up here around 3 p.m., and we were already here so I was happy," she said Monday.



Last year, some sale seekers became a little too excited and turned holiday shopping into a contact sport. In one ugly incident, a woman was accused of unleashing pepper spray on other shoppers in a dash for electronics at Walmart in Los Angeles.



This year, stores are beefing up security, and Best Buy even participated in training drills to handle the large crowds. More than 147 million people plan to shop this weekend, according to the National Retail Federation.



The hottest deals that are up for grabs this year include a 46-inch Samsung LED flat screen TV at Walmart with $200 off the original price. If that's not good enough, Sears has knocked $500 off the price of a 50-inch Toshiba flat screen. Target is offering the Nook Simple Touch at half price.



Black Friday officially kicks off at midnight for Best Buy, Sports Authority and Macy's.

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Cancer drug ads don’t boost inappropriate prescribing
















NEW YORK (Reuters Health) – A new study ties advertising for breast cancer drugs known as aromatase inhibitors to a slight increase in the total number of prescriptions for those medications.


But the extra prescriptions were limited to women with a medical reason for taking those drugs. The ads didn’t seem to increase the inappropriate use of aromatase inhibitors, which include letrozole (marketed as Femara) and anastrozole (Arimidex).













That’s in contrast to some previous studies that found so-called direct-to-consumer (DTC) advertising of antidepressants, for example, led to increases in prescriptions both for patients who needed them and those who didn’t.


“We know it increases demand for prescription drugs,” said Julie Donohue, a health policy researcher at the University of Pittsburgh who has studied direct-to-consumer advertising.


“What we don’t have a handle on is whether it’s stimulating primarily appropriate use or inappropriate use. Probably some combination, but we don’t know the ratio at all.”


Besides the United States, the only country that allows direct-to-consumer advertising is New Zealand, according to the World Health Organization. Top drugs marketed to patients include sleep aids and medications to treat high cholesterol.


Aromatase inhibitors are prescribed to older women who have had breast cancer to prevent it from coming back. Because they work by blocking the body from producing estrogen, the drugs aren’t supposed to be used in pre-menopausal women.


Tamoxifen is the drug of choice in younger women with hormone receptor positive breast cancer – the most common type – and an alternative to aromatase inhibitors in older women.


For the new study, researchers led by Dr. Gregory Abel from the Dana-Farber Cancer Institute in Boston compared drug companies’ monthly U.S. spending on direct-to-consumer ads for aromatase inhibitors with nationwide pharmacy data on the number of prescriptions for those drugs.


Between 2005 and 2007, spending on ads varied widely – from just over $ 22 million in October 2005 to less than $ 120,000 in January 2007.


Every million dollars spent over a month was tied to a 0.15-percent increase in aromatase inhibitor prescriptions three months later, the researchers reported in the journal Cancer.


However, when they looked specifically at older – likely post-menopausal – women and much younger women, ad spending was linked primarily to a rise in prescriptions for the older women.


A 0.18-percent increase in prescriptions for women over 60 accompanied every million ad dollars spent, but there was no increase among those 40 and younger.


Donohue, who wasn’t involved in the new study, said that in the case of aromatase inhibitors, it’s relatively easy for doctors to decide when it’s OK to prescribe the drugs, and for researchers to look back at patient records and figure out when the drugs were prescribed appropriately.


“It gets really tricky with something like depression,” she told Reuters Health – when the lines between minor and major depression can be blurry.


She said what doctors prescribe is often influenced by patient requests, with antibiotics being a prime example.


Donohue also pointed out that drug marketers not only print ads for doctors just as they do for potential patients, but they also send company representatives bearing free samples to visit doctors. That could also impact what doctors prescribe – and it’s not clear whether that was a factor in sales increases of aromatase inhibitors.


“While it is the most visible form of promotion, DTC is actually a smaller part of the marketing budget than advertising and other forms of promotion to physicians,” Donohue said.


“We can’t really know from this particular study which part of the equation was responsible for there not being inappropriate use. Was it that patients appropriately classified themselves and the women under 40 didn’t go to their doctors and ask (for aromatase inhibitors), or did doctors do the right thing for women under 40 and say ‘no?’”


SOURCE: http://bit.ly/TO4lSl Cancer, online November 6, 2012.


Medications/Drugs News Headlines – Yahoo! News



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Bank of Canada keeps “over time” condition on rate hike
















OTTAWA (Reuters) – Bank of Canada Deputy Governor Tim Lane repeated on Wednesday the central bank‘s message that interest rate increases will likely be needed, but only over time.


The “over time” phrase was introduced in the bank’s key guidance in its rate statement on October 23 as a way of signaling that while the next rate move is likely to be up, such a move was less imminent than it had been.













“Over time, some gradual withdrawal of monetary policy stimulus will likely be required, consistent with achieving the inflation-control target,” Lane said, according to a prepared presentation he was giving on Wednesday in Moncton, New Brunswick.


Another part of the presentation, which was posted on the central bank’s website, noted: “The Canadian economy continues to operate with a small amount of excess supply.”


The Bank of Canada is alone in the Group of Seven leading industrialized countries in signaling an intention to raise rates despite expectations of modest and unbalanced global growth.


Lane forecast “very robust growth” in emerging markets, stagnation in Europe and significant dampening of U.S. growth due to fiscal consolidation. He said Canada‘s real gross domestic product was still expected to grow at a moderate pace.


(Reporting by Randall Palmer; Editing by Jeffrey Hodgson; and Peter Galloway)


Canada News Headlines – Yahoo! News



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Rolling Stones aim to roll back years with reunion
















LONDON (Reuters) – The Rolling Stones return to the stage on Sunday for a mini-tour they hope will prove that advancing years and bad blood are no barriers to satisfaction for sellout crowds.


In a burst of activity to celebrate 50 years in business, the veteran British rockers with an average age of 68 have produced a photo book, written two songs, collaborated on a documentary, released a greatest hits album, played warm-up gigs in Paris and committed to five concerts.













They also faced questions about high ticket prices to the two gigs in London and three in the United States that have given some followers the impression they are more interested in banking cash than bashing out the hits.


Yet that has done little to dampen broad enthusiasm for their return to the big stage five years after the “A Bigger Bang” tour became the most lucrative in pop history at the time, earning nearly $ 560 million.


Adding to the sense of occasion, the full-time quartet of Mick Jagger on vocals, Keith Richards and Ronnie Wood on guitar and Charlie Watts on drums will be joined by former members Bill Wyman and Mick Taylor at London’s O2 Arena on Sunday.


Even before they step out for the first of two gigs in the British capital, the question on every Stones fan’s lips is what more they have up their sleeves, amid hints of a full tour and the possibility of a new studio album.


“It would be nice to think that wouldn’t be it,” said Paul Sexton, a music journalist who has met and interviewed the band in the run-up to the latest concerts.


“Once the machine gets fired up again, it’s hard to imagine there won’t be more live shows to come. If these dates went well, you could imagine sufficient momentum for some kind of recording project.”


BICKERING, BUT NO DIVORCE


The Stones first played at the Marquee Club in London in 1962, and with a changing lineup that settled with today’s foursome the band who had to compete with the Beatles quickly became one of the biggest groups in pop history.


Their blues-infused output slowed from the 1980s, and some critics argue they peaked in the 1960s and 70s, but the Stones’ longevity and a catalogue of hits like “(I Can’t Get No) Satisfaction”, “Jumpin’ Jack Flash” and “Honky Tonk Women” have ensured the music world still cares.


Despite the promise of a major payout and another chance to enhance their legacy, the 50th anniversary celebrations were not always a certainty.


Jagger and Richards have bickered in the past and were at it again recently with Richards calling the charismatic frontman “unbearable” amid a stream of insults in his 2010 memoir “Life”.


He eventually apologized, clearing the way for the reunion.


“If you was married to somebody for 50 years, you can have your little spats here and there, and we don’t mind having them in public occasionally,” the guitarist told Rolling Stone magazine. “We can’t get divorced – we’re doing it for the kids!”


The Stones will play two gigs at the O2 Arena, where tickets cost 95 to 950 pounds ($ 1,500) for a VIP seat, before crossing the Atlantic for a show at Barclay Center, Brooklyn on December 8 and two at the Prudential Center, Newark on December 13 and 15.


Jagger has been quick to defend the pricing, saying that the shows were expensive to stage and tickets being traded on secondary sites for greater than their face value did not mean more money for the band.


As to what the five concerts could lead to, Richards said in a recent interview: “My experience with the Rolling Stones is that once the juggernaut starts rolling, it ain’t gonna stop.”


Jagger and Richards are the only two members of the Stones who were there at its inception in 1962. Watts joined in early 1963 and Wood was recruited in the mid-1970s to replace Mick Taylor when he left.


They are widely acknowledged as the greatest rock and roll band in history, producing more than 20 studio albums, selling an estimated 200 million copies, conquering the United States and charting the social and sexual mores of their time.


Their longevity is all the more surprising given their reputation for living in the fast lane. Wood is in his third year of sobriety after struggling with alcohol addiction and Richards said he is drinking less and “gave up smack” (heroin).


(Reporting by Mike Collett-White)


Music News Headlines – Yahoo! News



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Greek PM presses for deal on loan
















ATHENS, Greece (AP) — Greece has reacted with dismay to the European Union‘s failure to agree to release vital rescue loan funds for the debt-ridden country, with the prime minister warning it was not just Greece’s future that hangs in the balance.


The delay prolongs uncertainty over the future of Greece, which faces a messy default that would threaten the entire euro currency used by 17 EU nations.













Prime Minister Antonis Samaras stressed that Greece has done what its creditors from the EU and International Monetary Fund required. “Our partners, along with the IMF, also must do what they have committed to doing,” he said.


He said that “it is not just the future of our country, but the stability of the entire eurozone” that depend on the success of negotiations in coming days.


Europe News Headlines – Yahoo! News



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New York Athletes Use Twitter to Gain Cult Hero Status
















If you’re one of the over 20.6 million Americans who has a Twitter account, chances are you’ve stumbled across the official SoccerGirlProblems Twitter handle, @SoccerGrlProbs, at least once while using the popular social media networking site.


SoccerGirlProblems, a feed spawned by three New York-based athletes, is a Twitter handle dedicated to the true-life outrageous complaints about everyday life as a high school or college soccer player.













The simple concept was started as a joke, but it has grown to startling dimensions.


SoccerGirlProblems has over 148,000 Twitter followers, and its explosive popularity led to the creation of a spinoff blog, a well-known YouTube account, a custom-made T-shirt business, and an official website.


Since opening in the beginning of 2012, the SoccerGirlProblems YouTube account has racked up over 3.2 million video views, and T-shirts have been selling like hotcakes. The SoccerGirlProblems Twitter page is also busier than ever, as it gained 50,000 new followers between May and November.


Punch #SGP or #SoccerGrlProbs into the Twitter search box on any given day, and you’ll immediately get a slew of hilarious tweets like “Took a long, hard stare at a pair of jeans this morning…Almost felt bad for neglecting them for so long. SWEATS IT IS,” along with other comedic gems like “family dreads thanksgiving if…i’m not on their team for flag football. Come on people what’s wrong with a little ‘friendly’ competition??”


With the SoccerGirlProblems brand finding so much success, one would expect the girls behind it to be household names by now, much like other Twitter/YouTube personalities like Jenna Marbles and Tay Zonday.


In fact, the founders of SoccerGirlProblems were afraid to reveal their identities until recently, as they feared retribution from conservative school administrators at their current school, Fairfield University.


The SoccerGirlProblems ladies believed that school officials from Fairfield would possibly find some of their hilarious tweets to be offensive or inappropriate. The founders did not want their tweets to bring negative exposure to their current or former schools.


It took over a year for the SoccerGirlProblems girls to reveal their identities publicly, but two of the three founders finally decided it was time to come out and detail how they became cult heroes via Twitter.


Carly Beyar, a South Hempstead, New York, resident and graduate of South Side High School in Rockville Centre, New York, along with Alanna Locast of Wantagh, New York, revealed that they are among the core group of tweeters handling the SoccerGirlProblems Twitter and YouTube accounts.


Locast, a graduate of Long Island’s Seaford High School, was an attacking offensive option for Fairfield until her graduation in 2011, while Beyar is still playing for the Fairfield Stags.


“It is still a shock to us that all of these girls relate to what we are saying,” Beyar said of her dedicated legion of Twitter followers in an exclusive online interview in May. “The soccer world is evidently a small one. It is comforting to know that we are not the only women soccer players out there dealing with these problems every day. Also, don’t get us wrong, we love soccer and will do anything for it; sometimes you just need to complain to keep you sane. ‘With training comes complaining.’”


Beyar and Locast, both standout high school soccer players on Long Island, think they can take SoccerGirlProblems to new heights due to the power of online marketing.


“I think it is easy to relate to our tweets when we are sarcastic and humorous,” Beyar said. “We try to take bothersome problems every day and turn it into something to just sit back and laugh about. We appreciate all of the support that our fans have given us since August. They are the best fans any Twitter account can ask for. Originally, we made this Twitter account for fun. We wanted to make it a team-based thing where everyone would tweet a problem from our team to get a laugh out of it. Little did we know how powerful the Web can be.”


Eric Holden covered the South Side Lady Cyclones girls’ soccer team in the 2010-11 season and has reported on Long Island soccer events since 2009. Follow him on Twitter @ericholden.


Social Media News Headlines – Yahoo! News



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A Minute With: Guillermo del Toro on “Rise of the Guardians”
















LOS ANGELES (Reuters) – Mexican filmmaker Guillermo del Toro is known for putting a dark twist on super heroes and children’s fantasy, but in “Rise of the Guardians” the producer brings together holiday heroes for a festive adventure.


Rise of the Guardians,” which will be in theaters on Friday, is based on award-winning author William Joyce’s “The Guardians of Childhood” books. In the film, traditional characters such as Santa Claus, Easter Bunny, Tooth Fairy, Sandman and Jack Frost join forces to save earth’s children from the evil Pitch Black and his band of Nightmares.













In the movie that stars Chris Pine, Alec Baldwin, Jude Law, Isla Fisher and Hugh Jackman, del Toro, 48, steps back into the executive producer role after directing dark fantasy “Pan’s Labyrinth” and the “Hellboy” superhero franchise.


He spoke to Reuters about putting his own stamp on beloved holiday heroes, and why children’s films are important to him.


Q: In “Rise of the Guardians,” Santa has tattoos, the Easter Bunny is Australian and the Tooth Fairy is half-human, half bird. Not the way most of us grew up imagining them, is it?


A: “We didn’t want the characters to have the affections that are given to them in certain cultures. We didn’t want to go with the safe Easter Bunny that is now a marketing tool … We wanted them to represent the world and to geographically make sense. Where would a burrower live, the Outback? The original incarnation of Santa is almost that of a hunter and wild man. It comes from the Nordic and Eastern European notions so we thought it would be great to make him Slavic.”


Q: The film is about addressing fear, which is always a challenging lesson for parents to teach their children. Why make this the central theme?


A: “In order to address fear, parents always end up tiptoeing around the subject. Shielding our kids is not the way to go, but you also don’t want to send them out unprepared without a healthy sense of self. I thought the movie was a great analogy to many things. It’s a great metaphor for kids to interpret the world.”


Q: What attracts you to the children’s genre?


A: “Some of my favorite authors in literature are guys that are great portrayers of childhood, but not necessarily childish – Mark Twain, Charles Dickens, Roald Dahl. And my movies like ‘Hellboy‘ and ‘Hellboy 2′ are about misfits coming together. Same with my Spanish movie ‘The Devil’s Backbone.’ So this movie is thematically very much within what I like to do.


“I think that for good or for bad, we spend the rest of our lives dealing with our first 13 years of life, trying to remedy or be lifted by whatever tools we were given when we were kids. Those first years are when we, as adults, sculpt the character of our kids … In reality, life puts kids in our lives for us to learn from them. There is no braver soul in the world than a kid.”


Q: Which “Guardian” do you identify with the most?


A: “I identify with North (Santa Claus). I have the greatest blessing in my life, which is the capacity to remain a child in the way I like to see the world. Like every artist, I have turmoil and I suffer. But ultimately I am able to find magic in the world. When North declares those principles, when he says ‘I feel it in my belly,’ it’s very much something I identify completely with.”


Q: Can we expect to see more of this band of heroes in future films?


A: “Obviously the possibility of telling another tale is completely dependent on the studio. But Bill Joyce has written many books on the characters and we are on board to create more and more adventures for them. We’ve been talking about some storylines. I am eager to tell everyone the story of North.”


Q: You recently finished shooting sci-fi adventure “Pacific Rim,” due in theaters in 2013, which is your first directing venture since 2008′s “Hellboy II: The Golden Army.” Why the break?


A: “I went to New Zealand to direct ‘The Hobbit’ and I was there for two years. I co-wrote the script, and at the end of the process there was a moment of decision where I really wanted to pursue something else and not keep waiting (‘The Hobbit’ production was delayed due to movie studio MGM’s financial troubles).


“Then I spent over a year trying to get a movie called ‘Mountains of Madness’ off the ground. That didn’t happen. Next it took another two years to get ‘Pacific Rim’ to the screen. But in the meantime, I co-wrote three novels, produced three movies and wrote a TV series. It’s been a very busy five years.”


(Reporting by Zorianna Kit, editing by Piya Sinha-Roy and Jeffrey Benkoe)


Movies News Headlines – Yahoo! News



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US abortions fall 5 pct, biggest drop in a decade
















NEW YORK (AP) — U.S. abortions fell 5 percent during the recession and its aftermath in the biggest one-year decrease in at least a decade, perhaps because women are more careful to use birth control when times are tough, researchers say.


The decline, detailed on Wednesday by the Centers for Disease Control and Prevention, came in 2009, the most recent year for which statistics are available. Both the number of abortions and the abortion rate dropped by the same percentage.













Some experts theorize that some women believed they couldn’t afford to get pregnant.


“They stick to straight and narrow … and they are more careful about birth control,” said Elizabeth Ananat, a Duke University assistant professor of public policy and economics who has researched abortions.


While many states have aggressively restricted access to abortion, most of those laws were adopted in the past two years and are not believed to have played a role in the decline.


Abortions have been dropping slightly over much of the past decade. But before this latest report, they seemed to have pretty much leveled off.


Nearly all states report abortion numbers to the federal government, but it’s voluntary. A few states — including California, which has the largest population and largest number of abortion providers — don’t send in data. While experts estimate there are more than 1 million abortions nationwide each year, the CDC counted about 785,000 in 2009 because of incomplete reporting.


To come up with reliable year-to-year comparisons, the CDC used the numbers from 43 states and two cities — those that have been sending in data consistently for at least 10 years. The researchers found that abortions per 1,000 women of child-bearing age fell from about 16 in 2008 to roughly 15 in 2009. That translates to nearly 38,000 fewer abortions in one year.


Mississippi had the lowest abortion rate, at 4 per 1,000 women of child-bearing age. The state also had only a couple of abortion providers and has the nation’s highest teen birth rate. New York, second to California in number of abortion providers, had the highest abortion rate, roughly eight times Mississippi’s.


Nationally since 2000, the number of reported abortions has dropped overall by about 6 percent and the abortion rate has fallen 7 percent.


By all accounts, contraception is playing a role in lowering the numbers.


Some experts cite a government study released earlier this year suggesting that about 60 percent of teenage girls who have sex use the most effective kinds of contraception, including the pill and patch. That’s up from the mid-1990s, when fewer than half were using the best kinds.


Experts also pointed to the growing use of IUDs, or intrauterine devices, T-shaped plastic sperm-killers that a doctor inserts into the uterus. A study released earlier this year by the Guttmacher Institute, a nonprofit organization that does research on reproductive health, showed that IUD use among sexually active women on birth control rose from less than 3 percent in 2002 to more than 8 percent in 2009.


IUDs essentially prevent “user error,” said Rachel Jones, a Guttmacher researcher.


Ananat said another factor may be the growing use of the morning-after pill, a form of emergency contraception that has been increasingly easier to get. It came onto the market in 1999 and in 2006 was approved for non-prescription sale to women 18 and older. In 2009 that was lowered to 17.


Underlying all this may be the economy, which was in recession from December 2007 until June 2009. Even well afterward, polls showed most Americans remained worried about anemic hiring, a depressed housing market and other problems.


You might think a bad economy would lead to more abortions by women who are struggling. However, John Santelli, a Columbia University professor of population and family health, said: “The economy seems to be having a fundamental effect on pregnancies, not abortions.”


More findings from the CDC:


— The majority of abortions are performed by the eighth week of pregnancy, when the fetus is about the size of a lima bean.


— White women had the lowest abortion rate, at about 8.5 per 1,000 women of child-bearing age; the rate for black women was about four times that. The rate for Hispanic women was about 19 per 1,000.


— About 85 percent of those who got abortions were unmarried.


— The CDC identified 12 abortion-related deaths in 2009.


Health News Headlines – Yahoo! News



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Obama praises Netanyahu on Gaza cease-fire

Egypt's Foreign Minister Mohamed Kamel Am, Secretary of State Hillary Clinton and Egypt's President Mohammed Morsi …President Barack Obama praised Israeli Prime Minister Benjamin Netanyahu on Wednesday for agreeing to an Egypt-crafted cease-fire with Palestinian militants in Gaza. Obama, speaking to Netanyahu by telephone, also underlined America's unwavering support for Israel's security and said he hoped to "intensify" U.S. assistance.


"The president commended the prime minister for agreeing to the Egyptian cease-fire proposal—which the president recommended the prime minister do—while reiterating that Israel maintains the right to defend itself," the White House said in a summary of the conversation.


Obama "expressed his appreciation for the prime minister's efforts to work with the new Egyptian government to achieve a sustainable cease-fire and a more durable solution to this problem," the White House said. Netanyahu initiated the call, according to an Obama aide.


The president's press office released the statement to reporters moments into a joint press conference in Cairo where Secretary of State Hillary Clinton and Egyptian Foreign Minister Mohamed Kamel Amr announced the cease-fire.


The emphasis on Egypt's role has been a cornerstone of the American effort ever since Israel answered persistent rocket fire by Gaza's Hamas rulers with punishing airstrikes in a steadily escalating conflict. The country shares a border with Gaza, and President Mohammed Morsi is seen in Washington as someone able to influence the militant Islamist organization's decision-making.


Obama also highlighted American backing of Israel. "The president made clear that no country can be expected to tolerate rocket attacks against civilians," the White House said.


"The president said that the United States would use the opportunity offered by a cease-fire to intensify efforts to help Israel address its security needs, especially the issue of the smuggling of weapons and explosives into Gaza," it said.


"The president said that he was committed to seeking additional funding for Iron Dome and other U.S.-Israel missile defense programs," the White House said.

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Facebook proposes to end voting on privacy issues
















NEW YORK (AP) — Facebook is proposing to end its practice of letting users vote on changes to its privacy policies. The company says it will continue to let users comment on proposed updates.


The world’s biggest social media company plans to announce Wednesday that its voting mechanism, which is triggered only if enough people comment on proposed changes, has become a system that emphasizes the quantity of responses over the quality of discussion.













Facebook began letting users vote on privacy changes in 2009. Since then, it has gone public and its user base has ballooned from around 200 million to more than 1 billion. As part of the 2009 policy, users’ votes only count if more than 30 percent of all Facebook’s active users partake.


Social Media News Headlines – Yahoo! News



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